Fighting Tanova

I'm at the start of chapter 3. I have been sent to the docks to talk to somebody at night. After resting at the inn until dark i head toward the southern docks and am immediately attacked by Tanova and two vampires. They ask about my working for the Shadow Thieves and then attack regardless of what I say. I put down the vamps easily enough but Tanova rips through my party with barely any effort. All my characters are carrying +2/+3 weapons but non of them are effective, no melee damage at all. I can do some damage with spell attacks but not enough before she kills us all. Am I missing something here. This battle seems WAY to tough for this point in the game. I cant even come close to beating her. Is there a trick to it or something?
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If it is an intended thing an, well, my memory fails, there are many encounters with female vampires in BG2, and some of them are highly difficult, while some are not.
Why don't you kill her with a mage using Staff of Magi?
Spell, hit (+4bonus), invisibilty, spell, hit, invisibility, etc...
Or if you want to be 100% sure, use a scroll of protection from undead. You can find them in almost every temple.
As for the staff, well...
Do you have a cleric in your party and if so what level are they?
To the OP: the vampire encounters are supposed to be very tough. In fact, they are likely to keep you indoors at night before you gain a few levels. However, as @CrevsDaak points out, Tanova should not be immune to +3 weapons, and I don't know what's going on in there. Sounds like some kind of bug to me. Try holy smite, flame arrow, all that. Since you are working for the Shadow thieves, you have been given an amulet that protects from level drain. Go to melee with somebody wearing that and cast all your spells with the rest of your group.
Her dire charm can also pose significant problems, so you should prepare. It IS a tough fight, if you're low-level.
A common solution to high weapon-immune creatures is the mage spell Melf's Minute Meteors, which always counts as +5 (or was it +6? can't remember... very high anyway), but it'll take a lot of arcane casters to get rid of 102 hp with 12 hp/round reg...
Maybe pick up Daystar and burn her with Sunray?
It is obvious that YOU didn't read what he said. Amulet of Power, sure...he is at the beginning of chap 3, more specifically he's doing the first quest with Mook.
You focus on your butthurting about the Staff without noticing I told him to use a
Scroll. Of. Protection. From. Undead.
It doesn't require an "experienced" player or any kind of tactic.
Lich and vampires are pieces of cake in vanilla just because of this op scroll.
It doesn't cost much, lasts 2hours and it is available in more than 10 places.
Just by using it on a char wielding a weapon +3 or more and sending him alone, he can kill Tanova without problems.
Now if you wanted to spam Fireballs against the vampire that would be a totally different story and it could work if done correctly.
After 20 or so tries, I went back to my auto-save, forcing to map to repopulate. The random encounter cleared and I was able to continue on without meeting her.
Finished the Chapter 3 storyline. Met her again in the crypts and took her down fairly easily (didn't actually kill her she turned into a bat and flew away) with normal tanking and ranged attacks/magic. Breach took her protections down like it's supposed to. I think her protections wee somehow stuck on and couldn't be dispelled or waited out.
All is well now.
Devil Shades are also pretty rough early in the game if you go to Hexxat's tomb right away, +2 weapons I believe to hit them and immune to all elemental damage.