Depends on the game and the creature involved. In IWD diseased status basically means the character will continue taking poison damage indefinitely unless they are cured. In BGEE/BG2EE it typically means you are taking poison damage over a given period of time. Occasionally though (like with Ghasts) the symbol will just mean a base Thac0 penalty.
I think you should be able to hover over the Icon/the text which says Diseased in the Record screen to see its exact effect. This would also help with poison (duration and damage/round) and a lot of other things.
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