Oh man good luck. I once spent 2 months trying to get BG to run on Vista. It may be doable, but probably not easy. My first recommendation would be to make sure it is NOT installed under program files. Compatibility mode MAY help. Good luck.
You could try using BG TUTU which will run the game in baldurs gate 2's engine which is somewhat happier with new operating systems. The original game is probably hopeless in win 10. Of course there is also BG:EE lol.
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ive tried comp mode.