Some of them didn't work out as well as I hoped but it's all about experimentation. I also used Waifu2x when I think I would get better results using ESRGAN, but I don't have the GPU to use ESRGAN with the size of these images. Waifu2x was trained on anime imagery which obviously doesn't translate well to the type of maps in Infinity Engine games.
Infinity Engine games mostly still look good today but I think they could still gain a slight benefit from upscaling, especially if you play with enhanced editions and use the zoom feature. We've been experimenting with other games at r/gameupscale as I think these upscaling algorithms have the potential to improve a lot of older games
I couldn't get them working properly in game though, but I've never worked with modding Infinity Engine games before. I think I'm incorrectly converting them back to TIF as the seams become very apparent.