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Stuck During Final Boss Fight (SPOILERS)
When you fight Jon Irenicus for the last time in BG2, he is supposed to initiate dialog with you when he's sufficiently low on health. After this dialog, the game's ending cutscene is triggered.
I have, however, managed to damage down Jon without him initiating dialog with me. I also couldn't initiate dialog with him. He just stands there with a neutral blue circle under him. Damaging him makes no difference either. This makes the game impossible to finish.
The steps to reproduce this issue are unknown to me, although I've been able to reproduce it twice. Dealing a lot of damage to Jon in a short time when he's low on life seems to help, though.
I would attach a saved game, but the game cannot be saved while this bug is present. (It says there are monsters nearby.)