First of all, most people are blowing things out of proportion. It's almost nothing... however...
The complaint in itself is right. It is not roleplay, it does not reflect the world of dungeon and dragon. A transgender person is someone that has a problem they cannot solve since as early as age 5. Now, if you are a DM, you sit at a table, books open, dice ready, and you invite a transgender person to play, who will that person play, the sex that person is in now, or the sex that person wants to be? The answer is the latter. That is why we only see gay or lesbians in DnD, never transgender.
There's some cursed belt but that's it, and it's just in the game as a joke to freak out players a little, nothing more.
This game does not deserve a rating of 0 just for that little oversight, of course. As previously stated, this is overblown. It's a troll wave/joke we've seen on Fallout 4, Dragon Age and Mass effect forums, and this troll wave will rear it's ugly head for many games to come.